Clinical characteristics, microbiology, and outcomes of infective endocarditis in Qatar

Clinical characteristics, microbiology, and outcomes of infective endocarditis in Qatar

Background: Infectious endocarditis (ie) is a serious and potentially fatal illness. Epidemiology, treatment options and results have changed considerably over the past two decades. The objective of the study was to describe epidemiology, clinical features and results of Qatar IE patients.

Methods: Patients were identified in the Hamad Medical Corporation Corporation’s electronic archives, the National Reference Center for Qatar State. We included 18-year-olds with a DUC diagnosis of DUC in the period from January 2015 to September 2017. Demographic and clinical data were recovered. Descriptive statistics were performed and a logistic regression analysis was used to describe the relationship between patient characteristics and hospital mortality. All potentially relevant variables have been included in the univariate analysis, while those with P <0,1 in the UNIVARIARY logistics regression model have been included in multivariate analysis. For the final template, we calculated dimension ratios (or) adjusted for each of the included variables, as well as their 95% confidence intervals (95% CI). The data was analyzed using Stata Software Version 15 (Statacorp, College Station, Texas, United States). The study was approved by the Council for Institutional Research with a renunciation of informed consent.

Results: Fifty-seven cases have been included, 70% of whom were men. The average age was 51 (± 16.8 years). Eleven (19%) were associated with prosthetic valves and 6 (11%) with implantable cardiac devices. Fever (84%), dyspnea (46%) and heart failure (37%) were the most common presentations. Only 58% of patients had pre-existing valvular heart disease or intracardiac. Cutaneous infections (10 patients, 18%) were the most common infection portals, followed by venous catheters, recent valve surgery and implantable heart devices. Staphylococci were involved in 19 (34%) and streptococcaceae in 9 patients (16%), while 21 patients (37%) were negative of culture. The target left (49 patients, 86%) was predominant.

 

Educational learning: mutual exchange between high school students and graduate students in the field of microbiology

The pedagogical learning process becomes more attractive when practical classes are used as part of methodological tools. Aim (i) stimulate the interest of high school students in the microbiological world and (ii) provide a didactic experience for graduate microbiology students, practical courses have been undertaken. These courses were conducted in the years 2016 and 2017, using the infrastructure held in Federal Viçosa Univeridade.

In short, laboratory classes have been prepared and taught by graduate microbiology students and an evaluation questionnaire has been answered by participants after classes. About 95% of high school students, two years, have evaluated the experience outside of the school routine as very good and good. A total of 90.09% (2016) and 100% (2017) graduate students evaluated this experience as good and good. The relationship between high school students and graduate students has also increased the curiosity of the first on the university environment.

As a result, the retention of information concerning the “world of microbiology” has been verified after one year and the students were able to remember the important terms related to the microbiology class. In addition, this work has allowed students graduate students and high school students to create a closer relationship and create an excellent pedagogical learning strategy for both.

 Clinical characteristics, microbiology, and outcomes of infective endocarditis in Qatar
Clinical characteristics, microbiology, and outcomes of infective endocarditis in Qatar

Tackling the pollution of real environmental paper: a microbiology lesson based on problems on carbon assimilation

Government and educational organizations advocate for the adoption of student-centered educational strategies in the Undergraduate programs. These strategies are known to benefit students by increasing performance and improving the control of the content of the class and increasing the content of the class and increasing the effect, particularly in students of racial / ethnic minorities underrepresented . Among these strategies, the case study and project-based learning allow students to master courses while collectively addressing relevant and real society issues. In particular, environmental pollution with paper-based products offers a microbiology problem on which microbiology students discover the role of microorganisms in paper waste management as well as microbiological and biochemical processes involved in the Secretion of proteins, the absorption of nutrients and energy metabolism.

Delivered in a hybrid class returned to an active learning laboratory (TEAL) activated by the technology, this lesson taught students about the secretion of exoenzyme, the hydrolysis of biopolymers, the intracellular transport of sugars and the catabolic reactions of sugar. Students have demonstrated an increased understanding of exoenzyme function and secretion, as well as how cells reach exoenzyme hydrolysis products. However, students had difficulty placing exoenzyme products transported in metabolic processes. Our results show increased perceived knowledge of students as well as understanding societal implications for these microbiological concepts. Our deviated lesson from knowledge silos in which students learn information in discrete topics.

Cefuroxime Sodium

C023-5G 5 g
EUR 335

Cefuroxime

GA9610-100MG 100 mg
EUR 70

Cefuroxime

GA9610-1G 1 g
EUR 156

Cefuroxime

GA9610-250MG 250 mg
EUR 94

Cromolyn sodium salt

SB0843 5g
EUR 65.66

Methotrexate sodium salt

M031-250MG 250 mg
EUR 117

Monensin Sodium Salt

M083-1G 1 g
EUR 71

Monensin Sodium Salt

M083-5x1G 5 x 1 g
EUR 159

MES, sodium salt

MB0611 50g
EUR 74.36

MOPSO, sodium salt

MDB0095 25g
EUR 63.92

MOPS, sodium salt

MDB360S 100g
EUR 89.15

Entacapone (sodium salt)

HY-14280A 10mg
EUR 119

Grazoprevir sodium salt

HY-15298C 10mg
EUR 243

Luminol (sodium salt)

HY-15922A 500mg
EUR 108

Salinomycin (sodium salt)

HY-17439 100mg
EUR 187

Heparin (sodium salt)

HY-17567A 500mg
EUR 147

Seladelpar sodium salt

HY-19522A 10mM/1mL
EUR 163

Etomoxir (sodium salt)

HY-50202A 5mg
EUR 147

Silmitasertib (sodium salt)

HY-50855B 10mg
EUR 187

Cefotaxime (sodium salt)

HY-A0088 10mM/1mL
EUR 113

Adapalene (sodium salt)

HY-B0091A 500mg
EUR 326

Cefoperazone (sodium salt)

HY-B0210A 500mg
EUR 108

Sulfamerazine (sodium salt)

HY-B0512A 500mg
EUR 131

Azlocillin (sodium salt)

HY-B0529A 500mg
EUR 113

Ceftriaxone (sodium salt)

HY-B0712B 500mg
EUR 173

Citicoline sodium salt

HY-B0739A 100mg
EUR 108

Bucladesine (sodium salt)

HY-B0764 50mg
EUR 139

Cloprostenol sodium salt

HY-108415 10mg
EUR 349

Fosmidomycin sodium salt

HY-112853 5mg
EUR 349

Zidebactam sodium salt

HY-120859A 10mg
EUR 1025

Resorufin sodium salt

HY-123533A 100mg
EUR 142

Batimastat (sodium salt)

HY-13564A 5mg
EUR 187

HEPES, sodium salt

HB0265 50g
EUR 65.66

HEPPSO, sodium salt

HB0496 25g
EUR 97.85

Nigericin (sodium salt)

HY-100381 100mg
EUR 725

Setogepram (sodium salt)

HY-100775 10mM/1mL
EUR 327

GJ103 (sodium salt)

HY-101203A 10mM/1mL
EUR 142

Moniliformin (sodium salt)

HY-101905 1mg
EUR 312

Danshensu (sodium salt)

HY-N0106 200mg
EUR 291

Monensin sodium salt

HY-N0150 100mg
EUR 108

XTT, sodium salt

PB2525 250mg
EUR 269.24

PIPES, sodium salt

PDB0434 100g
EUR 88.28

Suramin (sodium salt)

HY-B0879A 50mg
EUR 394

Zomepirac (sodium salt)

HY-B0890 500mg
EUR 160

Oxacillin (sodium salt)

HY-B0925 100mg
EUR 119

Methicillin (sodium salt)

HY-B0974 10mM/1mL
EUR 126

Sulfaquinoxaline sodium salt

HY-B1282A 100mg
EUR 119

Lorglumide sodium salt

HY-B1439B 5mg
EUR 119

Moxalactam (sodium salt)

HY-B1484 200mg
EUR 147

DIDS sodium salt

HY-D0086 50mg
EUR 142

NADP (sodium salt)

HY-F0002 500mg
EUR 271

TAPS, sodium salt

TB0920 50g
EUR 71.75

TAPSO, sodium salt

TB0922 50g
EUR 102.2

MES sodium salt

GB1926-10G 10 g
EUR 50

MES sodium salt

GB1926-250G 250 g
EUR 181

MES sodium salt

GB1926-500G 500 g
EUR 298

MOPSO sodium salt

GB3228-100G 100 g
EUR 94

MOPSO sodium salt

GB3228-25G 25 g
EUR 58

MOPSO sodium salt

GB3228-500G 500 g
EUR 229

TES sodium salt

GB4016-100G 100 g
EUR 150

TES sodium salt

GB4016-500G 500 g
EUR 429

CAPSO sodium salt

GB4515-100G 100 g
EUR 110

CAPSO sodium salt

GB4515-25G 25 g
EUR 54

CAPSO sodium salt

GB4515-500G 500 g
EUR 309

MOPS sodium salt

GB8397-100G 100 g
EUR 66

MOPS sodium salt

GB8397-1KG 1 kg
EUR 257

DIPSO sodium salt

GB8985-250G 250 g
EUR 628

BES sodium salt

GB9133-25G 25 g
EUR 86

HEPES sodium salt

GB9181-250G 250 g
EUR 99

HEPES sodium salt

GB9181-500G 500 g
EUR 150

Heparin sodium salt

GC2310-100MG 100 mg
EUR 46

Heparin sodium salt

GC2310-1G 1 g
EUR 82

Heparin sodium salt

GC2310-250MG 250 mg
EUR 54

XTT sodium salt

GC5281-100MG 100 mg
EUR 205

XTT sodium salt

GC5281-250MG 250 mg
EUR 325

XTT sodium salt

GC5281-25MG 25 mg
EUR 94

XTT sodium salt

GC5281-50MG 50 mg
EUR 142

Casein sodium salt

GE5861-100G 100 g
EUR 43

Casein sodium salt

GE5861-1KG 1 kg
EUR 70

Casein sodium salt

GE5861-250G 250 g
EUR 47

Casein sodium salt

GE5861-500G 500 g
EUR 54

TAPS sodium salt

GB0912-100G 100 g
EUR 134

TAPS sodium salt

GB0912-25G 25 g
EUR 62

TAPS sodium salt

GB0912-500G 500 g
EUR 341

TAPSO sodium salt

GB1759-100G 100 g
EUR 134

TAPSO sodium salt

GB1759-25G 25 g
EUR 62

MES sodium salt

GB1926-100G 100 g
EUR 110

MES sodium salt

GB1926-25G 25 g
EUR 62

MOPSO sodium salt

GB3228-250G 250 g
EUR 150

TES sodium salt

GB4016-250G 250 g
EUR 269

TES sodium salt

GB4016-25G 25 g
EUR 70

CAPSO sodium salt

GB4515-250G 250 g
EUR 205

MOPS sodium salt

GB8397-250G 250 g
EUR 104

MOPS sodium salt

GB8397-25G 25 g
EUR 49

MOPS sodium salt

GB8397-500G 500 g
EUR 161

DIPSO sodium salt

GB8985-100G 100 g
EUR 329

DIPSO sodium salt

GB8985-25G 25 g
EUR 150

BES sodium salt

GB9133-100G 100 g
EUR 181

BES sodium salt

GB9133-250G 250 g
EUR 341

HEPES sodium salt

GB9181-100G 100 g
EUR 70

HEPES sodium salt

GB9181-1KG 1 kg
EUR 229

HEPES sodium salt

GB9181-25G 25 g
EUR 54

Ceftizoxime sodium salt

GA1247-1G 1 g
EUR 82

Ceftizoxime sodium salt

GA1247-250MG 250 mg
EUR 59

Sulfamethazine sodium salt

GA1560-100G 100 g
EUR 86

Flucloxacillin sodium salt

GA1968-100MG 100 mg
EUR 229

Flucloxacillin sodium salt

GA1968-25MG 25 mg
EUR 110

Flucloxacillin sodium salt

GA1968-5MG 5 mg
EUR 62

Sulfathiazole sodium salt

GA2698-100G 100 g
EUR 126

Sulfathiazole sodium salt

GA2698-25G 25 g
EUR 62

Sulfamethoxazole sodium salt

GA2831-25G 25 g
EUR 94

Sulfamethoxazole sodium salt

GA2831-5G 5 g
EUR 58

Cefotaxime sodium salt

GA3583-1G 1 g
EUR 110

Cefotaxime sodium salt

GA3583-25G 25 g
EUR 500

Cefotaxime sodium salt

GA3583-5G 5 g
EUR 181

Piperacillin sodium salt

GA4134-1G 1 g
EUR 70

Piperacillin sodium salt

GA4134-5G 5 g
EUR 158

Cefoxitin sodium salt

GA4412-1G 1 g
EUR 110

Cefoxitin sodium salt

GA4412-250MG 250 mg
EUR 62

Cefoxitin sodium salt

GA4412-5G 5 g
EUR 293

Cefditoren sodium salt

GA4627-1G 1 g
EUR 628

Cloxacillin sodium salt

GA4688-1G 1 g
EUR 70

Cloxacillin sodium salt

GA4688-25G 25 g
EUR 421

While avoiding employing traditional and compartmentalized learning approaches, this student-centered guided lesson frames the systemic nature of the microbiological and biochemical processes underlying the decomposition of organic matter in a context of the real world. Anemia is a risk factor for negative results, which can be aggravated by unnecessary phlebotomies. In blood culture tests, up to 30 ml of blood can be removed by sample, although most manufacturers recommend blood volumes of 10 ml or less. After evaluating the volume of filling blood culture bottles in our institution, we investigated the question of whether an educational intervention could optimize the volume of blood culture bottles without negatively affecting microbiology tests.

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