Description: The IL-23RA:IL-23A[Biotin] Inhibitor Screening Assay Kit is designed for screening inhibitors of IL-23A:IL-23RA interaction. The key to this kit is the high sensitivity of detection of biotin-labeled IL-23A by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, IL-23RA is coated on a 96-well plate. Next, IL-23A[Biotin] is incubated with IL-23RA on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Description: The Mouse CTLA4[biotin]:B7-1 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of mouse CTLA4:B7-1 signaling. This kit comes in a convenient 96-well format, with biotin-labeled mouse CTLA4, purified mouse B7-1, streptavidin-labeled HRP, and assay buffer for 100 binding reactions. The key to this kit is the high sensitivity of detection of biotin-labeled mouse CTLA4 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, B7-1 is coated on a 96-well plate. Next, CTLA4[biotin] is incubated with B7-1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

Description: The IL-17RA:IL-17A[Biotin] Inhibitor Screening Assay Kit is designed for screening inhibitors of IL-17A:IL-17RA interaction. The key to this kit is the high sensitivity of detection of biotin-labeled IL-17A by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, IL-17RA is coated on a 96-well plate. Next, IL-17A[Biotin] is incubated with IL-17RA on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Description: The IL-17RA[Biotin]:IL-17A Inhibitor Screening Assay Kit is designed for_x000D_screening inhibitors of IL-17A:IL-17RA interaction. The IL-17RA[Biotin]-IL-17A Binding Assay Kit_x000D_comes in a convenient 96-well format, with biotin-labeled IL-17RA, purified IL-17A, streptavidinlabeled_x000D_HRP, and assay buffer for 100 binding reactions. The key to this kit is the high_x000D_sensitivity of detection of biotin-labeled IL-17RA by streptavidin-HRP. Only a few simple steps_x000D_on a microtiter plate are required for the assay. First, IL-17A is coated on a 96-well plate. Next,_x000D_IL-17RA is incubated with IL-17A on the plate. Finally, the plate is treated with streptavidin-HRP_x000D_followed by addition of an HRP substrate to produce chemiluminescence, which can then be_x000D_measured using a chemiluminescence reader.

Description: Cell signaling through the PD-1 receptor upon binding the PD-L1 ligand attenuates immune responses and is exploited by both tumors and viruses. The PD-1[Biotinylated]: PD-L1 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. This kit comes in a convenient 384-well format with biotin-labeled PD-1, purified PD-L1, streptavidin-labeled HRP, and assay buffer for 400 binding reactions. The key to this kit is the high sensitivity of detection of biotin-labeled PD-1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, PD-L1 is coated on a 384-well plate. Next, PD-1 is incubated with PD-L1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Description: The PD-1:PD-L1[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. The key to this kit is the high sensitivity of detection of biotin-labeled PD-L1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, PD-1 is coated on a 96-well plate. Next, PD-L1 is incubated with PD-1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Description: The PD-1:PD-L2[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. The key to this kit is the high sensitivity of detection of biotin-labeled PD-L2 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, PD-1 is coated on a 96-well plate. Next, PD-L2 is incubated with PD-1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Description: The PD-L1 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. The key to this kit is the high sensitivity of detection of biotin-labeled PD-1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, PD-L1 is coated on a 96-well plate. Next, PD-1 is incubated with PD-L1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Description: The PD-L2 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. The key to this kit is the high sensitivity of detection of biotin-labeled PD-1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, PD-L2 is coated on a 96-well plate. Next, PD-1 is incubated with PD-L2 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Description: The CD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD28:B7-1 signaling. The key to this kit is the high sensitivity of detection of biotin-labeled B7-1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, CD28 is coated on a 96-well plate. Next, B7-1 is incubated with CD28 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

Description: The PD-L1:B7-1[Biotinylated] Inhibitor Screening Assay Kit is designed for_x000D_screening and profiling inhibitors of the PD-L1:B7-1 interaction. The key to this kit is the high sensitivity of detection of_x000D_biotin-labeled B7-1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are_x000D_required for the assay. First, PD-L1 is coated on a 96-well plate. Next, B7-1-biotin is incubated_x000D_with PD-L1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition_x000D_of an HRP substrate to produce chemiluminescence, which can then be measured using a_x000D_chemiluminescence reader.

Description: The CD28:B7-2[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD28:B7-2 signaling. The key to this kit is the high sensitivity of detection of biotin-labeled B7-2 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, CD28 is coated on a 96-well plate. Next, B7-2 is incubated with CD28 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

Description: The CTLA4:B7-2[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CTLA4:B7-2-biotin interaction. The key to this kit is the high sensitivity of detection of CTLA4 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, CTLA4 is coated on a 96-well plate. Next, B7-2-biotin is incubated with CTLA4 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Description: The BAFF:BCMA[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of BAFF:BCMA signaling.The key to this kit is the high sensitivity of detection of biotin-labeled BCMA by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, BAFF is coated on a 96-well plate. Next, BCMA is incubated with BAFF on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

Description: The CD27:CD70[Biotinylated] Inhibitor Screening Assay Kit is designed for_x000D_ screening and profiling inhibitors of CD27:CD70 signaling. This kit comes in a convenient 96- well_x000D_ format, with biotin-labeled CD70, purified CD27, streptavidin-labeled HRP, and assay buffer for_x000D_100 binding reactions. The key to this kit is the high sensitivity of detection of biotin-labeled CD70_x000D_by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay._x000D_ First, CD27 is coated on a 96-well plate. Next, CD70 is incubated with CD27 on the plate. Finally,_x000D_ the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce_x000D_ chemiluminescence, which can be measured using a chemiluminescence reader.

Description: The LAG3:FGL1[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of LAG3:FGL1. The key to this kit is the high sensitivity of detection of biotin-labeled FGL1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, LAG3 is attached on a nickel-coated 96-well plate. Next, biotinylated FGL1 is incubated with LAG3 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.

Description: The activation of naíve T cells requires two signals, the specific T cell receptor recognition of MHC/Antigen on the surface of the antigen-presenting cell (APC), and the binding of B7-1 (CD80) ligand on the APC with the CD28 receptor on the T cell surface. Conversely, binding of CTLA4 to B7-1 on the T-cell surface results in an inhibitory signal and prevents T-cell activation. CTLA4B7-1 interaction is an important drug target for the regulation of the host's response to cancer. The CTLA4 [Biotinylated]:B7-1 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CTLA4:B7-1 signaling. The key to this kit is the high sensitivity of detection of biotin-labeled CTLA4 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, B7-1 is coated on a 96-well plate. Next, CTLA4[B] is incubated with B7-1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.