Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b

Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b

Background: GATA binding protein 3 (GATA3) and miR-29b associated with colorectal cancer (CRC). The current study explored the relationship between GATA3 and regulation of miR-29b, and the mechanism of drug resistance two in CRC cells to oxaliplatin.


Methods: Apoptosis CRC cells caused by oxaliplatin in various doses was detected by flow cytometry. CRC cells separately transfected with excess and knockdown of GATA3, agomir miR-29b and antagomir, and treated by oxaliplatin for the detection of cell viability and apoptosis by cell couting Kit-8 (CCK-8) and flow cytometry. The expression levels of GATA3, caspase3 and cleaved caspase3 determined by Western blot, and the expression of miR-29b was detected by real-time quantitative polymerase chain reaction (qRT-PCR). animal experiments were conducted to test the changes of transplanted tumor xenografts in nude mice studies and observed by in vivo imaging. TUNEL staining performed to detect apoptosis of tumor cells.


Results:
Both GATA3 and miR-29b agomir CRC inhibit the activity of cells, apoptosis is promoted and Cleaved caspase3 expression, and reduces cell resistance to chemotherapy drug oxaliplatin. Although GATA3 can up-regulate the expression of miR-29b, a tumor-suppression effects of GATA3 partially reversed by miR-29b antagomir. In vivo experiments showed that down-regulates expression of GATA3 promoted and the growth rate of transplanted tumor volume, while expressing GATA3 no significant effect on tumor growth. TUNEL staining results showed that knock down or overexpression of GATA3 not cause significant changes in the body of CRC cell apoptosis, while oxaliplatin treatment increases the number of apoptotic bodies.


Conclusion: GATA3 inhibit cell survival of CRC cells, promote apoptosis, and reduce oxaliplatin resistance of CRC cells through regulate miR-29b.

 Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b
Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b

Chloroquine Overcome Imatinib Resistance Combined with Imatinib in Gastrointestinal Stromal Tumors by Inhibiting Autophagy through the MAPK / ERK Pathway

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. However, up to 40-50% of GISTs develop secondary resistance after a median of 24 months of imatinib treatment. It has been reported that autophagy can promote cell survival and induces drug resistance GIST. Currently, the specific mechanism of autophagy in GISTs with imatinib resistance is not clear.


Materials and Methods: Cell-counting kit (CCK) -8 and flow cytometry method used for in vitro drug sensitivity testing and detection levels of autophagy. The detection rate of apoptosis is by flow cytometry with annexin V Kit. Western blotting was used to analyze the role of autophagy and apoptosis in GIST cells with CQ alone, imatinib alone, or in combination, and to analyze the expression of MAPK pathway.

In vitro results were confirmed by in vivo experiments using mouse models. Hematoxylin and eosin and immunohistochemical staining is used to detect pathological characteristics and immunophenotype transplanted tumor. Detection of KIT and PDGFRA gene mutations in imatinib-resistant GIST transplant performed by denaturing high-performance liquid chromatography (DHPLC) and direct sequencing. ERK and KIT expression and regulation of the level detected by Western blotting.

Rat Collagen Type IV(Col IV) Elisa Kit

EK720725 96 Wells
EUR 0.6

Fish Collagen Type IV (Col IV) ELISA Kit

AE49640FI-48Tests 48 Tests
EUR 360
Description: Fish

Fish Collagen Type IV (Col IV) ELISA Kit

AE49640FI-96Tests 96 Tests
EUR 680
Description: Fish

Human Collagen Type IV

GWB-14E8D9 0.5 mg Ask for price

Rat Collagen Type IV ELISA kit

E02C0047-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Collagen Type IV ELISA kit

E02C0047-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Collagen Type IV ELISA kit

E02C0047-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Collagen Type IV ELISA kit

E02C0780-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Rat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Collagen Type IV ELISA kit

E02C0780-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Rat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Collagen Type IV ELISA kit

E02C0780-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Rat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Collagen Type IV ELISA kit

E07C0047-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Collagen Type IV ELISA kit

E07C0047-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Collagen Type IV ELISA kit

E07C0047-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Collagen Type IV ELISA kit

E07C0780-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Porcine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Collagen Type IV ELISA kit

E07C0780-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Porcine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Collagen Type IV ELISA kit

E07C0780-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Porcine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Collagen Type IV ELISA kit

E08C0780-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Canine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Collagen Type IV ELISA kit

E08C0780-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Canine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Collagen Type IV ELISA kit

E08C0780-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Canine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Collagen Type IV ELISA kit

E08C0047-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Collagen Type IV ELISA kit

E08C0047-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Collagen Type IV ELISA kit

E08C0047-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Collagen Type IV ELISA kit

E01A10858 96T
EUR 700
Description: ELISA

Rat Collagen Type IV ELISA Kit

E01A11148 96T
EUR 700
Description: ELISA

Goat Collagen Type IV ELISA kit

E01A45770 96T
EUR 700
Description: ELISA

Goat Collagen Type IV ELISA Kit

E01A46061 96T
EUR 700
Description: ELISA

Goat Collagen Type IV ELISA kit

E06C0047-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Collagen Type IV ELISA kit

E06C0047-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Collagen Type IV ELISA kit

E06C0047-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Collagen Type IV ELISA kit

E06C0780-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Goat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Collagen Type IV ELISA kit

E06C0780-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Goat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Collagen Type IV ELISA kit

E06C0780-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Goat Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Collagen Type IV protein

30R-AC018 500 µg
EUR 641
Description: Purified native Human Collagen Type IV protein

Collagen Type IV protein

E62L004 1mg
EUR 875

Human Collagen Type IV ELISA kit

E01A2096 96T
EUR 700
Description: ELISA

Mouse Collagen Type IV ELISA kit

E01A19599 96T
EUR 700
Description: ELISA

Mouse Collagen Type IV ELISA Kit

E01A19889 96T
EUR 700
Description: ELISA

Human Collagen Type IV ELISA Kit

E01A2388 96T
EUR 700
Description: ELISA

Mouse Collagen Type IV ELISA kit

E03C0047-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Collagen Type IV ELISA kit

E03C0047-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Collagen Type IV ELISA kit

E03C0047-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Collagen Type IV ELISA kit

E03C0780-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Mouse Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Collagen Type IV ELISA kit

E03C0780-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Mouse Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Collagen Type IV ELISA kit

E03C0780-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Mouse Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Collagen Type IV ELISA kit

E01C0047-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Collagen Type IV ELISA kit

E01C0047-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Collagen Type IV ELISA kit

E01C0047-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Collagen Type IV ELISA kit

E01C0780-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Human Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Collagen Type IV ELISA kit

E01C0780-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Human Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Collagen Type IV ELISA kit

E01C0780-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Human Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep Collagen Type IV ELISA kit

E01A98063 96T
EUR 700
Description: ELISA

Sheep Collagen Type IV ELISA Kit

E01A98355 96T
EUR 700
Description: ELISA

Mouse Collagen Type IV ELISA KIT

ELA-E0180m 96 Tests
EUR 1038

Collagen Type IV antibody

10R-C137a 1 mL
EUR 520
Description: Mouse monoclonal Collagen Type IV antibody

Collagen Type IV antibody

10R-7847 100 ug
EUR 514
Description: Mouse monoclonal Collagen Type IV antibody

Collagen Type IV antibody

10R-7977 100 ug
EUR 492
Description: Mouse monoclonal Collagen Type IV antibody

Collagen Type IV antibody

20R-CR024 250 uL
EUR 532
Description: Rabbit polyclonal Collagen Type IV antibody

Collagen Type IV antibody

CAF50522-100ug 100ug
EUR 312

Collagen Type IV antibody

70R-CR013x 100 µg
EUR 1571
Description: Affinity purified Rabbit polyclonal Collagen Type IV antibody

Collagen Type IV Antibody

GWB-356560 1 ml Ask for price

Collagen Type IV Antibody

GWB-1DD386 0.1 mg Ask for price

Collagen Type IV Antibody

P1017-01m 0.1m
EUR 242.4

Collagen Type IV Antibody

P1017-1ml 1ml
EUR 685.2

Monkey Collagen Type IV ELISA kit

E01A71917 96T
EUR 700
Description: ELISA

Monkey Collagen Type IV ELISA Kit

E01A72207 96T
EUR 700
Description: ELISA

Canine Collagen Type IV ELISA kit

E01A63204 96T
EUR 700
Description: ELISA

Canine Collagen Type IV ELISA Kit

E01A63495 96T
EUR 700
Description: ELISA

Rabbit Collagen Type IV ELISA kit

E01A28338 96T
EUR 700
Description: ELISA

Rabbit Collagen Type IV ELISA Kit

E01A28629 96T
EUR 700
Description: ELISA

Bovine Collagen Type IV ELISA kit

E01A80634 96T
EUR 700
Description: ELISA

Bovine Collagen Type IV ELISA Kit

E01A80925 96T
EUR 700
Description: ELISA

Rabbit Collagen Type IV ELISA kit

E04C0780-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Rabbit Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Collagen Type IV ELISA kit

E04C0780-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Rabbit Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Collagen Type IV ELISA kit

E04C0780-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Rabbit Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Collagen Type IV ELISA kit

E04C0047-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Collagen Type IV ELISA kit

E04C0047-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Collagen Type IV ELISA kit

E04C0047-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Collagen Type IV ELISA kit

E09C0047-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Collagen Type IV ELISA kit

E09C0047-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Collagen Type IV ELISA kit

E09C0047-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Collagen Type IV ELISA kit

E09C0780-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Monkey Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Collagen Type IV ELISA kit

E09C0780-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Monkey Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Collagen Type IV ELISA kit

E09C0780-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Monkey Collagen Type IV in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Collagen Type IV ELISA Kit

ELA-E0180Mo 96 Tests
EUR 1113.6

Porcine Collagen Type IV ELISA kit

E01A54487 96T
EUR 700
Description: ELISA

Porcine Collagen Type IV ELISA Kit

E01A54778 96T
EUR 700
Description: ELISA

Chicken Collagen Type IV ELISA kit

E01A89360 96T
EUR 700
Description: ELISA

Chicken Collagen Type IV ELISA Kit

E01A89649 96T
EUR 700
Description: ELISA

Slides Staining Jar, Hellendhal Type

CG145-5X1NO 1 unit
EUR 61.59
Description: Slides Staining Jar, Hellendhal Type

Rat Collagen Type IV (COL4) CLIA Kit

abx196379-96tests 96 tests
EUR 990

Pig Collagen Type IV (COL4) CLIA Kit

20-abx496628
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Collagen Type IV (COL4) CLIA Kit

20-abx491198
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  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

CLIA Kit for Collagen Type IV (COL4)

SCA180Hu 96Т
EUR 840

Rat Collagen Type IV (COL4) CLIA Kit

abx196379-100g 100 µg Ask for price

Rat Collagen Type IV (COL4) CLIA Kit

abx196379-50g 50 µg
EUR 618.75

Pig Collagen Type IV (COL4) ELISA Kit

20-abx585246
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  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Collagen Type IV (COL4) ELISA Kit

20-abx155378
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  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Collagen Type IV (COL4) ELISA Kit

abx256822-96tests 96 tests
EUR 904.8

Pig Collagen Type IV (COL4) ELISA Kit

abx361367-96tests 96 tests
EUR 990

Rat Collagen Type IV (COL4) ELISA Kit

EKN44434-48T 48T
EUR 370.02

Rat Collagen Type IV (COL4) ELISA Kit

EKN44434-5x96T 5x96T
EUR 2510.85

Rat Collagen Type IV (COL4) ELISA Kit

EKN44434-96T 96T
EUR 528.6

Pig Collagen Type IV (COL4) ELISA Kit

EKU10735-48T 48T
EUR 600.25

Pig Collagen Type IV (COL4) ELISA Kit

EKU10735-5x96T 5x96T
EUR 4073.13

Pig Collagen Type IV (COL4) ELISA Kit

EKU10735-96T 96T
EUR 857.5

Rat Collagen Type IV (COL4) ELISA Kit

EKU03323-48T 48T
EUR 542.78

Rat Collagen Type IV (COL4) ELISA Kit

EKU03323-5x96T 5x96T
EUR 3683.15

Rat Collagen Type IV (COL4) ELISA Kit

EKU03323-96T 96T
EUR 775.4

Pig Collagen Type IV (COL4) ELISA Kit

EKN51846-48T 48T
EUR 373.38

Pig Collagen Type IV (COL4) ELISA Kit

EKN51846-5x96T 5x96T
EUR 2533.65

Pig Collagen Type IV (COL4) ELISA Kit

EKN51846-96T 96T
EUR 533.4

Rat COL4(Collagen Type IV) ELISA Kit

ELK1712-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat COL4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat COL4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat COL4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat COL4 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat COL4(Collagen Type IV) ELISA Kit

ELK1712-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat COL4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat COL4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat COL4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat COL4 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat Collagen Type IV (COL4) ELISA Kit

NSL1551r 96 Tests
EUR 498

Rat Collagen Type IV ELISA Kit (COL4)

RK03583 96 Tests
EUR 625.2

ELISA Kit for Collagen Type IV (COL4)

SEA180Hu 96Т
EUR 630

ELISA Kit for Collagen Type IV (COL4)

SEA180Mu 96Т
EUR 648

ELISA Kit for Collagen Type IV (COL4)

SEA180Po 96Т
EUR 756

for Collagen Type IV (COL4)ELISA kit

SEA180Po-10x96wellstestplate 10x96-wells test plate
EUR 6117.62
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Collagen Type IV (COL4) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

for Collagen Type IV (COL4)ELISA kit

SEA180Po-1x48wellstestplate 1x48-wells test plate
EUR 608.98
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Collagen Type IV (COL4) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

for Collagen Type IV (COL4)ELISA kit

SEA180Po-1x96wellstestplate 1x96-wells test plate
EUR 818.54
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Collagen Type IV (COL4) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

for Collagen Type IV (COL4)ELISA kit

SEA180Po-5x96wellstestplate 5x96-wells test plate
EUR 3323.45
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of for Collagen Type IV (COL4) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

ELISA Kit for Collagen Type IV (COL4)

4-SEA180Po
  • Ask for price
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Collagen Type IV (COL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA Kit for Collagen Type IV (COL4)

SEA180Ra 96Т
EUR 684

Rat Collagen Type IV (COL4) ELISA Kit

SEA180Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Collagen Type IV (COL4) in serum, plasma, tissue homogenates and other biological fluids.

Rat Collagen Type IV (COL4) ELISA Kit

SEA180Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Collagen Type IV (COL4) in serum, plasma, tissue homogenates and other biological fluids.

Rat Collagen Type IV (COL4) ELISA Kit

SEA180Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Collagen Type IV (COL4) in serum, plasma, tissue homogenates and other biological fluids.

Rat Collagen Type IV (COL4) ELISA Kit

SEA180Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Collagen Type IV (COL4) in serum, plasma, tissue homogenates and other biological fluids.

Rat Collagen Type IV (COL4) ELISA Kit

4-SEA180Ra
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Collagen Type IV (COL4) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Collagen Type IV (COL4) ELISA Kit

abx155378-1mg 1 mg
EUR 675

Cow Collagen Type IV (COL4) ELISA Kit

abx585646-100g 100 µg
EUR 6700

Cow Collagen Type IV (COL4) ELISA Kit

abx585646-10g 10 µg
EUR 743.75

Cow Collagen Type IV (COL4) ELISA Kit

abx585646-50g 50 µg
EUR 3537.5

Human Collagen Type IV (COL4) CLIA Kit

20-abx190890
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Collagen Type IV (COL4) CLIA Kit

abx196377-96tests 96 tests
EUR 990

Mouse Collagen Type IV (COL4) CLIA Kit

abx196378-96tests 96 tests
EUR 990

Mouse Collagen Type IV (COL4) CLIA Kit

20-abx491197
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  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Collagen Type IV (COL4) CLIA Kit

EKU08857-48T 48T
EUR 666.82

Human Collagen Type IV (COL4) CLIA Kit

EKU08857-5x96T 5x96T
EUR 4524.85

Human Collagen Type IV (COL4) CLIA Kit

EKU08857-96T 96T
EUR 952.6

Human Collagen Type IV (COL4) CLIA Kit

EKN49968-48T 48T
EUR 414.89

Human Collagen Type IV (COL4) CLIA Kit

EKN49968-5x96T 5x96T
EUR 2815.33

Human Collagen Type IV (COL4) CLIA Kit

EKN49968-96T 96T
EUR 592.7

Goat Collagen Type IV(COL4) ELISA Kit

NSL0896Gt 96T
EUR 528

Human Collagen Type IV (COL4)CLIA Kit

SCA180Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Collagen Type IV (COL4) in serum, plasma, tissue homogenates and other biological fluids.

Human Collagen Type IV (COL4)CLIA Kit

SCA180Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Collagen Type IV (COL4) in serum, plasma, tissue homogenates and other biological fluids.

Human Collagen Type IV (COL4)CLIA Kit

SCA180Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Collagen Type IV (COL4) in serum, plasma, tissue homogenates and other biological fluids.

Human Collagen Type IV (COL4)CLIA Kit

SCA180Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Collagen Type IV (COL4) in serum, plasma, tissue homogenates and other biological fluids.

Human Collagen Type IV (COL4) CLIA Kit

4-SCA180Hu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Collagen Type IV (COL4)Serum, plasma, tissue homogenates and other biological fluids

Human Collagen Type IV (COL4) CLIA Kit

abx196377-100g 100 µg Ask for price

Human Collagen Type IV (COL4) CLIA Kit

abx196377-50g 50 µg
EUR 618.75

Mouse Collagen Type IV (COL4) CLIA Kit

abx196378-100g 100 µg Ask for price

Mouse Collagen Type IV (COL4) CLIA Kit

abx196378-50g 50 µg
EUR 618.75

Human Collagen Type IV (COL4) ELISA Kit

20-abx151127
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  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Collagen Type IV (COL4) ELISA Kit

abx255284-96tests 96 tests
EUR 848.4

Human Collagen Type IV (COL4) ELISA Kit

abx252254-96tests 96 tests
EUR 848.4

Mouse Collagen Type IV (COL4) ELISA Kit

20-abx153851
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  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Sheep Collagen Type IV (COL4) ELISA Kit

abx364200-96tests 96 tests
EUR 1111.2

Human COL4(Collagen Type IV) ELISA Kit

EH2867 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Mouse COL4(Collagen Type IV) ELISA Kit

EKF58219-48T 48T
EUR 396.9

Mouse COL4(Collagen Type IV) ELISA Kit

EKF58219-5x96T 5x96T
EUR 2693.25

Mouse COL4(Collagen Type IV) ELISA Kit

EKF58219-96T 96T
EUR 567

Human Collagen Type IV (COL4) ELISA Kit

EKN44432-48T 48T
EUR 341.04

Human Collagen Type IV (COL4) ELISA Kit

EKN44432-5x96T 5x96T
EUR 2314.2

Human Collagen Type IV (COL4) ELISA Kit

EKN44432-96T 96T
EUR 487.2

Mouse Collagen Type IV (COL4) ELISA Kit

EKN44433-48T 48T
EUR 350.42

Mouse Collagen Type IV (COL4) ELISA Kit

EKN44433-5x96T 5x96T
EUR 2377.85

Mouse Collagen Type IV (COL4) ELISA Kit

EKN44433-96T 96T
EUR 500.6

Human COL4(Collagen Type IV) ELISA Kit

EKF57575-48T 48T
EUR 396.9

Human COL4(Collagen Type IV) ELISA Kit

EKF57575-5x96T 5x96T
EUR 2693.25

Human COL4(Collagen Type IV) ELISA Kit

EKF57575-96T 96T
EUR 567

Human Collagen Type IV (COL4) ELISA Kit

EKU11878-48T 48T
EUR 550.34

Human Collagen Type IV (COL4) ELISA Kit

EKU11878-5x96T 5x96T
EUR 3734.45

Human Collagen Type IV (COL4) ELISA Kit

EKU11878-96T 96T
EUR 786.2

Human Collagen Type IV (COL4) ELISA Kit

EKU03321-48T 48T
EUR 500.5

Human Collagen Type IV (COL4) ELISA Kit

EKU03321-5x96T 5x96T
EUR 3396.25

Human Collagen Type IV (COL4) ELISA Kit

EKU03321-96T 96T
EUR 715

Mouse Collagen Type IV (COL4) ELISA Kit

EKU03322-48T 48T
EUR 514.08

Mouse Collagen Type IV (COL4) ELISA Kit

EKU03322-5x96T 5x96T
EUR 3488.4

Mouse Collagen Type IV (COL4) ELISA Kit

EKU03322-96T 96T
EUR 734.4

Human Collagen Type IV (COL4) ELISA Kit

EKN52989-48T 48T
EUR 342.3

Human Collagen Type IV (COL4) ELISA Kit

EKN52989-5x96T 5x96T
EUR 2322.75

Human Collagen Type IV (COL4) ELISA Kit

EKN52989-96T 96T
EUR 489

Human Collagen Type IV (COL4) ELISA Kit

EK11636 96Т
EUR 799

Human Collagen Type IV (COL4) ELISA Kit

AE61389HU-48Tests 48 Tests
EUR 360
Description: Human (Homo sapiens)

Human Collagen Type IV (COL4) ELISA Kit

AE61389HU-96Tests 96 Tests
EUR 680
Description: Human (Homo sapiens)

Human COL4(Collagen Type IV) ELISA Kit

ELK2331-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human COL4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human COL4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human COL4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human COL4 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human COL4(Collagen Type IV) ELISA Kit

ELK2331-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human COL4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human COL4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human COL4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human COL4 in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse COL4(Collagen Type IV) ELISA Kit

ELK1665-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse COL4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse COL4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse COL4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse COL4 in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse COL4(Collagen Type IV) ELISA Kit

ELK1665-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse COL4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse COL4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse COL4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse COL4 in the samples is then determined by comparing the OD of the samples to the standard curve.


Results
: In vitro and in vivo experiments, the level of imatinib-resistant cell autophagy higher than normal cells; CQ combined with imatinib may promote apoptosis by blocking the imatinib-resistant cell autophagy. Meanwhile, we found that the levels of ERK phosphorylation may be associated with autophagy.

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