Overexpression of LRRC59 Is Associated with Poor Prognosis and Promotes Cell Proliferation and Invasion in Lung Adenocarcinoma

Overexpression of LRRC59 Is Associated with Poor Prognosis and Promotes Cell Proliferation and Invasion in Lung Adenocarcinoma

Objective: LRRC59 (leucine-rich repeat-containing protein 59) is a ribosome-binding protein which also interacts with the fibroblast growth factor. limited investigation reveals the possibility of LRRC59 role in aggressive phenotype of breast cancer. However, if LRRC59 contribute to the development of lung cancer is still unclear.


Materials and Methods: In this study, a software-based survival analysis TCGA online (GEPIA2) was used to estimate the prognostic value LRRC59 mRNA expression levels for lung cancer. Cells Counting Kit-8 assay, colony-forming assay, cell cycle analysis, and transwell test used to assess the biological function LRRC59 in lung cancer cells. Then, 94 lung adenocarcinoma (LUAD) patient tissue were collected to test the level LRRC59 expression by tissue microarray (TMA) based immunohistochemical staining (IHC). Kaplan-Meier univariate and multivariate Cox regression analysis was performed to evaluate the prognostic value of protein expression in LUAD LRRC59.


Results: High Level of LRRC59 mRNA was significantly associated with poorer survival for lung adenocarcinoma, but not for lung squamous cell carcinoma. ShRNA knockdown of LRRC59 by apparently inhibiting cell proliferation and colony formation in both H1299 and A549 cells. G1 / S phase arrest caused by depletion LRRC59 observed in A549 and H1299 cells. In addition, silencing LRRC59 decreased migrative cells and invasive ability. In addition, the TMA-based IHC showed that it was highly expressed in LRRC59 LUAD network and closely associated with lymph node metastasis (P <0.001), TNM stage (P <0.001), and histological differentiation (P = 0.007). Further multivariate analysis showed that excessive LRRC59 an independent prognostic factor in LUAD.


Conclusion: LRRC59 can serve as novel biomarkers and therapeutic targets for clinical practice LUAD.

 Overexpression of LRRC59 Is Associated with Poor Prognosis and Promotes Cell Proliferation and Invasion in Lung Adenocarcinoma
Overexpression of LRRC59 Is Associated with Poor Prognosis and Promotes Cell Proliferation and Invasion in Lung Adenocarcinoma

LncRNA MIR4435-2HG inhibit the progression of osteoarthritis through sponges mir-510-3p

Osteoarthritis (OA) is a joint disorder diarthrodial which can have several causes. Long non-coding RNA (lncRNAs) participated in several diseases, including OA. Recently reported that microRNA lncRNA 4435-2HG (MIR4435-2HG) is downregulated in OA tissue; However, the biological role during the progression of OA MIR4435-2HG still unclear. In this study, interleukin (IL) -1β used to build an in vitro model of OA. protein expression of matrix metallopeptidase (MMP) 1, MMP13, collagen II, interleukin (IL) -17A, p65, phosphorylated (p) -p65, IκB and p-IκB in CHON-001 cells were detected by western blotting.

Gene expression of IL-17A, and miR-510-3p MIR4435-2HG network or CHON-001 cells was measured by reverse transcription-quantitative PCR and western blotting, respectively. Cells Counting Kit-8 assay and immunofluorescence staining were used to investigate cell proliferation, and cell apoptosis was detected by flow cytometry. The relationship between MIR4435-2HG, miR-510-3p and IL-17A was investigated using a dual luciferase assay report. MIR4435-2HG and excess miR-510-3p CHON-transfected into 001 cells.

The results show that excess miR4435-2HG significantly increase proliferation and inhibit apoptosis CHON-001 cells. In addition, miR-510-3p identified as a downstream target MIR4435-2HG, and miR-510-3p directly targeted IL-17A. The results of this study indicate that MIR4435-2HG can mediate the development of OA by disabling NF-kB signaling pathway.

Coomassie Brilliant Blue Gel Staining Kit

abx090653-1Kit 1 Kit
EUR 226.8

SafePinky DNA Gel Staining Solution

S1000-050 500ml
EUR 157.2

SafePinky DNA Gel Staining Solution

S1000-100 2X500ml
EUR 225.6

SafePinky DNA Gel Staining Solution

S1000-200 4X500ml
EUR 336

Gelite™ Green Nucleic Acid Gel Staining Kit

17589 1 Kit
EUR 262.8

Gelite™ Orange Nucleic Acid Gel Staining Kit

17594 1 Kit
EUR 262.8

Prosi Silver Staining Kit for 25 mini gel

S3200-020 1kit
EUR 433.2

DAB Enhancer for ampliying DAB stains in IHC staining, 60ml

NB308 60 ml
EUR 512.4

DAB Enhancer for ampliying DAB stains in IHC staining, 30ml

NB308-30 30 ml
EUR 358.8

dsGreen Gel Staining Solution, 10000×, 0.5 mL

10010 0.5 mL
EUR 106.8

dsGreen Gel Staining Solution, 10000×, 50 uL

A0010 50 uL
EUR 62.4

SafePinky DNA Gel Staining Solution(10,000X) In Water

S1001-025 250ul
EUR 193.2

SafePinky DNA Gel Staining Solution(10,000X) In Water

S1001-050 2x250ul
EUR 296.4

SafePinky DNA Gel Staining Solution(10,000X) In Water

S1001-100 1ml
EUR 522

SafePinky DNA Gel Staining Solution(10,000X) In Water

S1001-500 5x1ml
EUR 1971.6

Safe E-Red DNA Gel Staining Solution(1000x)

S1002-001 1ml
EUR 133.2

Safe E-Red DNA Gel Staining Solution(1000x)

S1002-005 5x1ml
EUR 271.2

Safe E-Red DNA Gel Staining Solution(1000x)

S1002-010 10ml
EUR 360

Safe E-Red DNA Gel Staining Solution(1000x)

S1002-020 20ml
EUR 595.2

ProLite™ His-Tag Protein Gel Staining Kit *Green Fluorescence*

18010 10 Gels
EUR 412

Leukemia - ALL Exosome

P141-ALL - Ask for price

Leukemia - ALL Exosome RNA

P241-ALL - Ask for price

DAPI Staining Kit

abx097206-1Kit 1 Kit
EUR 276

PI Staining Kit

abx097208-1Kit 1 Kit
EUR 276

?-Galactosidase Staining Kit

AKR-100 1 kit
EUR 518.4
Description: This simple assay measures the transfection efficiency of the LacZ gene using a simple staining protocol.

Pesticide Kit Containing All 10 Multi-Compound Mixes

SPXPR-KIT 1ML
EUR 1923.18

Beta Galactosidase Staining Kit

55R-1541 250 assays
EUR 444
Description: Assay Kit for detection of Beta Galactosidase in the research laboratory

CometAssay Silver Staining Kit

4254-200-K 200 Tests
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Hoechst 33342 Staining Kit

abx097207-1Kit 1 Kit
EUR 276

Human Histochemistry Staining Kit

20-abx299039
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  • EUR 678.00
  • 150 tests
  • 500 tests
  • 50 tests

Beta-Galactosidase Staining Kit

K802-250
EUR 352.8

Alkaline Phosphatase Staining Kit

K2035-50 50 assays
EUR 454.8

Beta-Galactosidase Staining Kit

K2182-250 250 assays
EUR 351.6

Maximo-Gel juice fluorescent Protein-Gel Gel stain

310012 10 ml
EUR 222

Maximo-Gel juice fluorescent Protein-Gel Gel stain

310012-L 10x10ml
EUR 1904.4

Gel-Bright LED Gel Illuminator

E90003 1EA
EUR 927.6
Description: Minimum order quantity: 1 unit of 1EA

Canadian Pesticide Kit Containing All 6 Mixes

CAN-CAN-KIT 1ML
EUR 758.1

Quick Gel Extraction Kit

20-abx098085
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  • 200 rxns
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Gel DNA Recovery Kit

GP05 5 preps Ask for price

Gel DNA Recovery Kit

GP100 100 preps
EUR 156

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GP200 200 preps
EUR 226.8

Gel DNA Recovery Kit

GP50 50 preps
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AmbiClean Kit (PCR & Gel)

GV05 5 preps Ask for price

AmbiClean Kit (PCR & Gel)

GV100 100 preps
EUR 153.6

AmbiClean Kit (PCR & Gel)

GV200 200 preps
EUR 226.8

AmbiClean Kit (PCR & Gel)

GV50 50 preps
EUR 109.2

Frit Kit

FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Nerve Terminal Staining Kit V

70034 1SET
EUR 610.8
Description: Minimum order quantity: 1 unit of 1SET

CaspGLOW Active Caspase Staining Kit

55R-1292 25 assays
EUR 355.2
Description: Caspase Staining Kit for use activity in the research laboratory

Live/Dead Cell Staining Kit

55R-1434 100 tests
EUR 765.6
Description: Live/Dead Cell Staining Kit for use in the research laboratory

Blue-Color AP Staining Kit

AP100B-1 50 Assays
EUR 314.4

Dual- Color AP Staining Kit

AP100D-1 100 Assays
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Red-Color AP Staining Kit

AP100R-1 50 Assays
EUR 314.4

Live-Dead Cell Staining Kit

K2081-100 100 staining
EUR 552

DNA Ploidy Analysis Staining Kit

K1439-1
EUR 705.6

DNA Ploidy Analysis Staining Kit

K1439-5
EUR 2402.4

Fluorescein Active Caspase Staining Kit

K2047-100 100 assays
EUR 686.4

Fluorescein Active Caspase Staining Kit

K2047-25 25 assays
EUR 285.6

Red Active Caspase Staining Kit

K2052-100 100 assays
EUR 686.4

Red Active Caspase Staining Kit

K2052-25 25 assays
EUR 285.6

Live-Dead Cell Staining Kit

K501-100
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Column Packing Kit

PACK-KIT 1pack
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Gel Tray

2394250 4unit
EUR 324
Description: I ncl udi ng pl at es

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2398194 2unit
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TC Gel

CP048-005 500 g
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TC Gel

CP048-010 1 Kg
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Gel Cutter

KS071012-11 12
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Gel Filter

KS071012-13 12
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PCR Mycoplasma Detection Kit

M034-Kit Kit
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2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)

GEN-402-25tests 25 tests
EUR 292.8
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1332

AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE620A-KIT 1 kit
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SDS-PAGE Gel Preparation Kit

abx090646-1Kit 1 Kit
EUR 243.6

Gel Extraction Kit (100 preps)

9K-006-0001 100preps
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9K-006-0002 200preps, 200prep
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ISOLATE II PCR & Gel Kit

BIO-52058 10 preps Ask for price

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SDS-PAGE Gel Preparation Kit

AR0138 1kit (Enough for 30-50 pieces of gel.)
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GEL Purification Mini Kit (50prep)

FAGPK-001 50 preps
EUR 144

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FAGPK-001-1 200 preps
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FAGPK-001-2 300 preps
EUR 226.8

MicroElute GEL Purification Kit (50prep)

FAMGK-001 50 preps
EUR 151.2

MicroElute GEL Purification Kit (200prep)

FAMGK-001-1 200 preps
EUR 224.4

Zenoquick Gel DNA Recovery Kit

Z3001-050 50 preps
EUR 238.8

Zenoquick Gel DNA Recovery Kit

Z3001-200 4x50 preps
EUR 757.2

Gel Filtration LMW Calibration Kit

28403841 EACH
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Gel Filtration HMW Calibration Kit

28403842 EACH
EUR 603.06

FitAmp Gel DNA Isolation Kit

P-1007 100 Samples
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CaspGLOW Active Caspase 12 Staining Kit

55R-1291 25 assays
EUR 338.4
Description: Caspase 12 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 2 Staining Kit

55R-1293 25 assays
EUR 340.8
Description: Caspase 2 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 3 Staining Kit

55R-1294 25 assays
EUR 355.2
Description: Caspase 3 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 8 Staining Kit

55R-1295 25 assays
EUR 355.2
Description: Caspase 8 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 9 Staining Kit

55R-1296 25 assays
EUR 355.2
Description: Caspase 9 Staining Kit for use activity in the research laboratory

CaspGLOW Red Active Caspase Staining Kit

55R-1297 25 assays
EUR 355.2
Description: Caspase Staining Kit for use activity in the research laboratory

Yeast Viability Staining Kit (Green/Red)

31063-1 1kit
EUR 566.4
Description: Minimum order quantity: 1 unit of 1kit

Human Type I Collagen Staining Kit

9044 1 kit
EUR 406.26
Description: Human Type I Collagen Staining Kit

Hoechst 33342 / PI Double Staining Kit

abx097209-1Kit 1 Kit
EUR 292.8

Alcian Blue (pH 2.5) Staining Kit

AFR-1 250 ml ea.
EUR 249.6

Alcian Blue (pH 2.5) Staining Kit

AFR-2 30 ml ea.
EUR 153.6

StemTAG Alkaline Phosphatase Staining Kit (Red)

CBA-300 100 assays
EUR 553.2
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Staining Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining.

StemTAG Alkaline Phosphatase Staining Kit (Purple)

CBA-306 100 assays
EUR 553.2
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Staining Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining.

Human FoxP3 Transcription Factor Staining Kit

OKTA00001 KIT
EUR 544.8
Description: Description of target: ;Species reactivity: ;Application: FC;Assay info: ;Sensitivity:

Human FoxP3 Transcription Factor Staining Kit

OKTA00004 KIT
EUR 544.8
Description: Description of target: ;Species reactivity: ;Application: FC;Assay info: ;Sensitivity:

CaspGLOW? Fluorescein Active Caspase Staining Kit

K180-100
EUR 660

CaspGLOW? Fluorescein Active Caspase Staining Kit

K180-25
EUR 280.8

Genorise® Alkaline Phosphatase Staining Kit

GR107045 100 tests
EUR 346.8

Fluorescein Active Caspase-12 Staining Kit

K2046-100 100 assays
EUR 686.4

Fluorescein Active Caspase-12 Staining Kit

K2046-25 25 assays
EUR 285.6

Fluorescein Active Caspase-2 Staining Kit

K2048-100 100 assays
EUR 686.4

Fluorescein Active Caspase-2 Staining Kit

K2048-25 25 assays
EUR 285.6

Fluorescein Active Caspase-3 Staining Kit

K2049-100 100 assays
EUR 686.4

Fluorescein Active Caspase-3 Staining Kit

K2049-25 25 assays
EUR 285.6

Fluorescein Active Caspase-8 Staining Kit

K2050-100 100 assays
EUR 686.4

Fluorescein Active Caspase-8 Staining Kit

K2050-25 25 assays
EUR 285.6

Fluorescein Active Caspase-9 Staining Kit

K2051-100 100 assays
EUR 686.4

Fluorescein Active Caspase-9 Staining Kit

K2051-25 25 assays
EUR 285.6

Red Active Caspase-3 Staining Kit

K2053-100 100 assays
EUR 686.4

Red Active Caspase-3 Staining Kit

K2053-25 25 assays
EUR 285.6

Red Active Caspase-8 Staining Kit

K2054-100 100 assays
EUR 686.4

Red Active Caspase-8 Staining Kit

K2054-25 25 assays
EUR 285.6

Red Active Caspase-9 Staining Kit

K2055-100 100 assays
EUR 686.4

Red Active Caspase-9 Staining Kit

K2055-25 25 assays
EUR 285.6

Lipid (Oil Red O) staining Kit

K580-24
EUR 542.4

CaspGLOW? Red Active Caspase Staining Kit

K190-100
EUR 627.6

CaspGLOW? Red Active Caspase Staining Kit

K190-25
EUR 288

Stayright™ Purple HRP Staining Kit

45905 5 mL
EUR 109

Stayright™ Purple HRP Staining Kit

45906 50 mL
EUR 334

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1358.4

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1358.4

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1358.4

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1358.4

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1358.4

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 966

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1358.4

AGAR, HIGH GEL

A01-102IHG-10kg 10 kg
EUR 2662.8

AGAR, HIGH GEL

A01-102IHG-2Kg 2 Kg
EUR 625.2

AGAR, HIGH GEL

A01-102IHG-500g 500 g
EUR 213.6

Gel tray L

2322112 5unit
EUR 308.4
Description: 2pcs/1set

Gel tray S

2322117 5unit
EUR 308.4
Description: 2pcs/1set

Ketanserin (Vulketan Gel)

E1KS2232 50mg
EUR 520.8

Gel Breaker Tubes

KS071012-12 12
EUR 106.8
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

ViSafe RED Gel

S430 500 µl
EUR 175.2

ViSafe RED Gel

S430L 5x500 µl
EUR 668.4

ViSafe Green Gel

S435 500 µl
EUR 175.2

ViSafe Green Gel

S435L 5x500 µl
EUR 668.4

Aluminium Phosphate Gel

VAdv-Ly0001 250 mL
EUR 1663.2
Description: Aluminium Phosphate Gel 2%, Aluminum salt Vaccine adjuvant.

Aluminium Hydroxide Gel

VAdv-Ly0003 250 mL
EUR 1663.2
Description: Aluminium Hydroxide Gel 2%, Aluminum salt Vaccine adjuvant.

Gel Casting Tray

ELE8158 EACH
EUR 87.78

Gel electrode Hanna

HI-12170 EACH
EUR 174.42

Gel Cushioned Insole

SAF7748 PR
EUR 11.63

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1358.4

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 183.6

PI / RNase Staining Buffer

20-abx090619
  • EUR 326.40
  • EUR 276.00
  • 100 tests
  • 50 tests

Ponceau S Staining Solution

B7778-100000 100 g
EUR 195.6

Ponceau S Staining Solution

B7778-50000 50 g
EUR 151.2

EasyDip Slide Staining System

M900-12AS-ASSORTED 1 Case(s)
EUR 211.2

SDS-PAGE Staining Solution

GR103068 100 mL
EUR 69.6

Ponceau S Staining Solution

PW005 100ml
EUR 82.97

Disposable Slide Staining Trays

MIC5070 PK4
EUR 71.82

Staining Trough+Lid Rectangular

MIC6008 EACH
EUR 23.03

Nalgene Box Staining 13x13x5cm

BOX1040 EACH
EUR 42.18

Claritas PPT Grade Minerals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL

SPXMT-KIT 30ML
EUR 237.12

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 5929.2

Claritas PPT Grade Heavy Metals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL

SPXHM-KIT 30ML
EUR 245.1

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 5929.2

DNA Gel Extraction Kit - 250 Columns

31030-250 1kit
EUR 654
Description: Minimum order quantity: 1 unit of 1kit

DNA Gel Extraction Kit - 50 Columns

31030-50 1kit
EUR 186
Description: Minimum order quantity: 1 unit of 1kit

LumiPure DNA Gel Extraction Kit, 50

23793 50 preps
EUR 90

FastPure Gel DNA Extraction Mini Kit

DC301-01 100 rxn
EUR 154.8

Gel and PCR DNA Purification kit

K1455-250 250 Preps
EUR 576

Gel and PCR DNA Purification kit

K1455-50 50 Preps
EUR 247.2

MicroElute GEL/PCR Purification Kit (50prep)

FAEPK-001 50 preps
EUR 157.2

MicroElute GEL/PCR Purification Kit (200prep)

FAEPK-001-1 200 preps
EUR 249.6

MicroElute GEL/PCR Purification Kit (300prep)

FAEPK-001-2 300 preps
EUR 274.8

GEL/PCR Purification Mini Kit (100prep)

FAGCK-001 100 preps
EUR 154.8

GEL/PCR Purification Mini Kit (300prep)

FAGCK-001-1 300 preps
EUR 206.4

Protein Extraction Kit from Gel Slices

P519-20 - Ask for price

Protein Extraction Kit from Gel Slices

P519-80 - Ask for price

HF Antidote Gel First Response Kit

SAF9640 EACH
EUR 21.66

CaspGLOW Red Active Caspase 3 Staining Kit

55R-1298 25 assays
EUR 355.2
Description: Caspase 3 Staining Kit for use activity in the research laboratory

CaspGLOW Red Active Caspase 8 Staining Kit

55R-1299 25 assays
EUR 355.2
Description: Caspase 8 Staining Kit for use activity in the research laboratory

CaspGLOW Red Active Caspase 9 Staining Kit

55R-1300 25 assays
EUR 355.2
Description: Caspase 9 Staining Kit for use activity in the research laboratory

In addition, excess miR4435-2HG inhibit the development of OA, indicating that miR4435-2HG can be considered as a potential therapeutic target in OA.

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