Ischaemic preconditioning-induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway

Ischaemic preconditioning-induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway

Ischemia / reperfusion (I / R) injury can cause severe arrhythmias and myocardial damage worsens. Exosomes are small membrane vesicles that play a protective role of injury I / R myocardium. This study aims to explore the protective effects of ischemic preconditioning (IPC) induced serum exosomes (IPC-Ex) on the injury I / R myocardium in rats and the underlying mechanism. serum exosomes derived from rats IPC and quantified using bicinchoninic acid assay kit. IPC-Exo (50 mg) injected into the myocardium infarction immediately after the ligation. Rats were randomly divided into Sham, I / R, IPC-Ex + I / R, I / R + LY294002, and I / R + group IPC-Ex + LY294002. hemodynamic parameters measured by physiological recording.

Transthoracic echocardiography is used to detect heart function. Serum levels of creatine kinase-MB isomers, lactate dehydrogenase, aspartate transaminase, tumor necrosis factor-alpha, interleukin (IL) -1β, and IL-10 were detected by enzyme-linked immunosorbent assay. Triphenyl tetrazolium chloride staining was used to measure the size of myocardial infarction. Apoptosis in myocardial tissue was detected by TUNEL staining. Western blotting was used to detect the level of PI3K / AKT and proteins associated with apoptosis.

The results of our study indicate that treatment with IPC-Ex improved heart function and reduce the production of inflammatory factors, cardiomyocyte apoptosis, and myocardial infarct size. In addition, the IPC-Ex treatment promoted protein expression of Bcl-2, p-PI3K and p-AKT but inhibited the caspase-3 and Bax. However, treatment with LY294002 significantly reverse the increase in p-PI3K and p-AKT levels, hemodynamic improvement, and decreased production of inflammatory factor and apoptosis in group I / R + IPC IPC-Exo-Exo-induced. Taken together, our results suggest that the IPC-Ex can reduce the injury I / R via activating PI3K / AKT signaling pathway.

 Ischaemic preconditioning-induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway
Ischaemic preconditioning-induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway

Tanshinone IIA ameliorates the development of CAD Through Heart Settings H9c2 Cell Proliferation and Apoptosis by miR-133a-3p / EGFR Axis

Background: Coronary artery disease (CAD) leads to the world of death, serious threat to human health. Tanshinone IIA (Tan IIA), which can be extracted from Danshen, applied in the treatment of cardiovascular and cerebrovascular diseases. MicroRNAs (miRNAs, Mirs) plays an important role in cell proliferation and apoptosis of cells of the cardiovascular system. The purpose of this study was to explore the role of Tan IIA in CAD in vitro and the underlying molecular mechanisms.


Methods: Real-time polymerase chain reaction (RT-PCR) and Western blot used to detect miRNA / mRNA and protein, respectively. target genes miR-133a-3p searched at TargetScan and targeting relationships verified by dual-luciferase reporter assay. Cell proliferation was determined using cells Counting Kit-8 (CCK-8) and Edu labeling. Cell apoptosis was detected by flow cytometry and TUNEL staining.


Results: In this study, lower levels of miR-133a-3p and epidermal growth factor receptor that is higher (EGFR, the target of miR-133a-3p) level found in H2O2-induced cell H9c2. In addition, Tan IIA-regulated miR-133a-3p and downregulated the expression of EGFR. In addition, Tan IIA promoted cell proliferation and reduced apoptosis and increased G0 / G1, which is reversed with inhibitors of miR-133a-3p, while siRNA-EGFR eliminate the effects caused by miR-133a-3p in H2O2-induced cell H9c2.

StemTAG Alkaline Phosphatase Staining Kit (Red)

CBA-300 100 assays
EUR 553.2
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Staining Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining.

StemTAG Alkaline Phosphatase Staining Kit (Purple)

CBA-306 100 assays
EUR 553.2
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Staining Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining.

Cellular Senescence Detection Kit (SA-?-Gal Staining)

CBA-230 50 assays
EUR 622.8
Description: Our Cellular Senescence Staining Kit provides an efficient method to visualize Senescence Associated (SA) ß-galactosidase. SA-ß-Gal catalyzes the hydrolysis of X-gal, which produces a blue color in senescent cells. Visualize results with a standard light microscope.

Cellular Senescence Detection Kit (SA-?-Gal Staining)

CBA-230-5 5 x 50 assays
EUR 2461.2
Description: Our Cellular Senescence Staining Kit provides an efficient method to visualize Senescence Associated (SA) ß-galactosidase. SA-ß-Gal catalyzes the hydrolysis of X-gal, which produces a blue color in senescent cells. Visualize results with a standard light microscope.

OxiSelect DNA Double-Strand Break (DSB) Staining Kit

STA-321 100 assays
EUR 790.8
Description: Double-strand breaks (DSB) in DNA are among the most dangerous types of DNA damage occuring within cells. One of the earliest cellular responses to double-strand breaks is the phosphorylation of a histone variant, H2AX, at the sites of DNA damage. Within seconds Ser139 is phosphorylated when DSBs are induced in mammalian cells. Phosphorylation of this serine residue causes chromatin condensation and appears to play a critical role in the recruitment of repair or damage-signaling factors to the DNA damage sites. The OxiSelect DNA Double-Strand Break Staining Kit provides an easy-to-use method for detecting the presence of DSBs in cells cultured in microtiter plates. Double strand breaks can be detected in just a few hours by immunofluorescence staining of the phosphorylated histone H2AX.

StemTAG Alkaline Phosphatase Staining and Activity Assay Kit, Colorimetric

CBA-302 2 x 100 assays
EUR 769.2
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StemTAG Alkaline Phosphatase Staining and Activity Assay Kit, Fluorometric

CBA-308 2 x 100 assays
EUR 846
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Activity Assay Combo Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining as well as in a 96-well plate with either colorimetric or fluorescence detection.

OxiSelect Cellular UV-Induced DNA Damage Staining Kit (CPD)

STA-327 96 assays
EUR 790.8
Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of cyclobutane pyrimidine dimers (CPD) by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-CPD antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope.

OxiSelect DNA Double Strand Break (DSB) Staining Kit, Trial Size

STA-321-T 20 assays
EUR 421.2
Description: Double-strand breaks (DSB) in DNA are among the most dangerous types of DNA damage occuring within cells. One of the earliest cellular responses to double-strand breaks is the phosphorylation of a histone variant, H2AX, at the sites of DNA damage. Within seconds Ser139 is phosphorylated when DSBs are induced in mammalian cells. Phosphorylation of this serine residue causes chromatin condensation and appears to play a critical role in the recruitment of repair or damage-signaling factors to the DNA damage sites. The OxiSelect DNA Double-Strand Break Staining Kit provides an easy-to-use method for detecting the presence of DSBs in cells cultured in microtiter plates. Double strand breaks can be detected in just a few hours by immunofluorescence staining of the phosphorylated histone H2AX.

OxiSelect Cellular UV-Induced DNA Damage Staining Kit (6-4PP)

STA-329 96 assays
EUR 790.8
Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of 6-4PP structures in DNA by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-6-4PP antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope.

OxiSelect Cellular UV-Induced DNA Damage Staining Kit (CPD), Trial Size

STA-327-T 32 assays
EUR 421.2
Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of cyclobutane pyrimidine dimers (CPD) by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-CPD antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope.

Live/Dead Cell Staining Kit

55R-1434 100 tests
EUR 765.6
Description: Live/Dead Cell Staining Kit for use in the research laboratory

Live-Dead Cell Staining Kit

K2081-100 100 staining
EUR 552

Live-Dead Cell Staining Kit

K501-100 each
EUR 561.6

OxiSelect Cellular UV-Induced DNA Damage Staining Kit (6-4PP), Trial Size

STA-329-T 32 assays
EUR 421.2
Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of 6-4PP structures in DNA by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-6-4PP antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope.

DAPI Staining Kit

abx097206-1Kit 1 Kit
EUR 276

PI Staining Kit

abx097208-1Kit 1 Kit
EUR 276

Beta Hexosaminidase Activity Assay Kit

MET-5095 100 assays
EUR 609.6

Cell Navigator® Live Cell Tubulin Staining Kit

23170 100 Slides
EUR 222

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23171 300 Slides
EUR 446

Autophagy/Cytotoxicity Dual Staining Kit (Cell-Based)

K449-50 each
EUR 652.8

Lysosomal Cytotoxicity Dual Staining Kit (Cell-Based)

K458-50 each
EUR 686.4

EZCell? Intracellular Zinc Staining Kit (Cell-Based)

K525-50 each
EUR 679.2

CometAssay Silver Staining Kit

4254-200-K 200 Tests
EUR 390.96

Hoechst 33342 Staining Kit

abx097207-1Kit 1 Kit
EUR 276

Human Histochemistry Staining Kit

20-abx299039
  • EUR 1045.20
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  • EUR 678.00
  • 150 tests
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Alkaline Phosphatase Staining Kit

K2035-50 50 assays
EUR 454.8

Human Beta 2 Microglobulin ELISA Kit

PRB-5038 96 assays
EUR 686.4
Description: Our Human Beta 2 Microglobulin ELISA Kit is a sandwich ELISA for the detection of human beta 2 microglobulin in plasma, serum, lysates, and other biological fluids. Samples or standards are added to an anti-b2M antibody coated plate followed by the addition of an HRP conjugated anti-human b2M antibody. The absorbance is read at 450nm and the level of b2M in samples is determined based on the provided human b2M standard curve.

Beta-Hydroxybutyrate (Ketone Body) Assay Kit (Colorimetric)

MET-5082 100 assays
EUR 609.6

Beta-Hydroxybutyrate (Ketone Body) Assay Kit (Fluorometric)

MET-5083 100 assays
EUR 609.6

Fluorescent Particle Kit

FA-2552-6K 6x1 mL
EUR 554.4
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FX-3552-9K 9X1 mL
EUR 675.6
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Cell Navigator™ Mitochondrion Staining Kit *Blue Fluorescence*

22665 500 Assays
EUR 262.8

Cell Navigator™ Mitochondrion Staining Kit *Green Fluorescence*

22666 500 Assays
EUR 262.8

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22667 500 Assays
EUR 262.8

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22668 500 Assays
EUR 262.8

Cell Navigator™ Mitochondrion Staining Kit *NIR Fluorescence*

22670 500 Assays
EUR 262.8

Cell Navigator™ Lysosome Staining Kit *NIR Fluorescence*

22652 500 Tests
EUR 262.8

Cell Navigator™ Lysosome Staining Kit *Blue Fluorescence*

22655 500 Tests
EUR 211.2

Cell Navigator™ Lysosome Staining Kit *Green Fluorescence*

22656 500 Tests
EUR 211.2

Cell Navigator™ Lysosome Staining Kit *Orange Fluorescence*

22657 500 Tests
EUR 211.2

Cell Navigator™ Lysosome Staining Kit *Red Fluorescence*

22658 500 Tests
EUR 211.2

Fluorescent

FPAK-3058--9K 9X1 mL
EUR 675.6
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Frit Kit

FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

CaspGLOW Active Caspase Staining Kit

55R-1292 25 assays
EUR 355.2
Description: Caspase Staining Kit for use activity in the research laboratory

Nerve Terminal Staining Kit V

70034 1SET
EUR 610.8
Description: Minimum order quantity: 1 unit of 1SET

Blue-Color AP Staining Kit

AP100B-1 50 Assays
EUR 314.4

Dual- Color AP Staining Kit

AP100D-1 100 Assays
EUR 494.4

Red-Color AP Staining Kit

AP100R-1 50 Assays
EUR 314.4

Fluorescein Active Caspase Staining Kit

K2047-100 100 assays
EUR 686.4

Fluorescein Active Caspase Staining Kit

K2047-25 25 assays
EUR 285.6

Red Active Caspase Staining Kit

K2052-100 100 assays
EUR 686.4

Red Active Caspase Staining Kit

K2052-25 25 assays
EUR 285.6

Purple-Color AP Staining Kit

AP100P-1 100 Assays
EUR 235

DNA Ploidy Analysis Staining Kit

K1439-1 each
EUR 705.6

DNA Ploidy Analysis Staining Kit

K1439-5 each
EUR 2402.4

Cell Navigator™ Cell Plasma Membrane Staining Kit *Orange Fluorescence*

22680 500 Tests
EUR 262.8

Cell Navigator™ Cell Plasma Membrane Staining Kit *Red Fluorescence*

22681 500 Tests
EUR 262.8

Cell Navigator® Cell Plasma Membrane Staining Kit *Green Fluorescence*

22682 500 Tests
EUR 222

Column Packing Kit

PACK-KIT 1pack
EUR 1242
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 319.2

Cell Navigator™ Mitochondrion Staining Kit *Deep Red Fluorescence*

22669 500 Assays
EUR 262.8

Cell Navigator™ Lysosome Staining Kit *Deep Red Fluorescence*

22659 500 Tests
EUR 211.2

Carboxyl Fluorescent Particle Kit

CFA-2552-6K 6x1 mL
EUR 554.4
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFA-2558-6K 6x1 mL
EUR 554.4
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFA-3558-6K 6x1 mL
EUR 554.4
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFB-2552-6K 6x1 mL
EUR 554.4
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFB-2558-6K 6x1 mL
EUR 554.4
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFB-3558-6K 6x1 mL
EUR 554.4
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particles Kit

CFX-3552-9K 9X1 mL
EUR 687.6
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

AccuCount Fluorescent Particle Kit

ACFP-50-4K 4X1mL
EUR 620.4
Description: Flow Cytometry Particles For Absolute Cell Counting

EasyComp Fluorescent Particles Kit

ECFP-K1 mL
EUR 358.8
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EasyComp Fluorescent Particles Kit

ECFP-K2 mL
EUR 444
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EasyComp Fluorescent Particles Kit

ECFP-K3 mL
EUR 444
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EasyComp Fluorescent Particles Kit

ECFP-K4 mL
EUR 700.8
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EasyComp Fluorescent Particles Kit

ECFP-K5 mL
EUR 639.6
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Fluorescent Particle Array Kit

FPAK-4058--10K 10 mL
EUR 675.6
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Glutathione Reductase Fluorescent Kit

K009-F1 1x96 well plate
EUR 418.8

Thiol Fluorescent Detection Kit

K005-F1 1x96 well plate
EUR 381.6

Glutathione Fluorescent Detection Kit

K006-F1 1x96 well plate
EUR 424.8

Biotin Fluorescent Particle Kit

TFA-3558-6K 6x1 mL
EUR 554.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Biotin Fluorescent Particle Kit

TFB-3558-6K 6x1 mL
EUR 554.4
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Streptavidin Fluorescent Particle Kit

SVFA-2552--6K 6x1 mL
EUR 554.4
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Streptavidin Fluorescent Particle Kit

SVFA-2558--6K 6x1 mL
EUR 554.4
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Streptavidin Fluorescent Particle Kit

SVFB-2552--6K 6x1 mL
EUR 554.4
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Streptavidin Fluorescent Particle Kit

SVFB-2558--6K 6x1 mL
EUR 554.4
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ADAM17 Fluorescent Assay Kit

78000 96 rxns.
EUR 465
Description: The ADAM17 Fluorescent Assay Kit is provided in a convenient 96-well format, with purified ADAM17, ADAM Fluorogenic Substrate, and ADAM assay buffer for 96 enzyme reactions. The key to the ADAM17 Fluorescent Assay Kit is the fluorogenic substrate. Using this kit, only one simple step on a microtiter plate is required for ADAM17 reactions. A sample containing ADAM17 is incubated in a reaction mixture with the fluorogenic substrate and fluorescence (λex=358±10 nm, λem=455±10 nm) is measured using a plate reader.

TMPRSS2 Fluorescent Assay Kit

78083 96 rxns.
EUR 1205
Description: The key to the TMPRSS2 Fluorescent Assay Kit is the fluorogenic substrate. Using this kit, only one simple step on a microtiter plate is required for TMPRSS2 reactions. A sample containing TMPRSS2 is incubated in a reaction mixture with the fluorogenic substrate and fluorescence (λex=383nm, λem=455nm) is measured using a plate reader. Camostat is supplied as a protease inhibitor control.

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1332

Pesticide Kit Containing All 10 Multi-Compound Mixes

SPXPR-KIT 1ML
EUR 1923.18

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS410A-KIT 1 kit (10 rxn)
EUR 798

Alcian Blue (pH 2.5) Staining Kit

AFR-1 250 ml ea.
EUR 249.6

Alcian Blue (pH 2.5) Staining Kit

AFR-2 30 ml ea.
EUR 153.6

CaspGLOW Active Caspase 12 Staining Kit

55R-1291 25 assays
EUR 338.4
Description: Caspase 12 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 2 Staining Kit

55R-1293 25 assays
EUR 340.8
Description: Caspase 2 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 3 Staining Kit

55R-1294 25 assays
EUR 355.2
Description: Caspase 3 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 8 Staining Kit

55R-1295 25 assays
EUR 355.2
Description: Caspase 8 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 9 Staining Kit

55R-1296 25 assays
EUR 355.2
Description: Caspase 9 Staining Kit for use activity in the research laboratory

CaspGLOW Red Active Caspase Staining Kit

55R-1297 25 assays
EUR 355.2
Description: Caspase Staining Kit for use activity in the research laboratory

Human Type I Collagen Staining Kit

9044 1 kit
EUR 406.26
Description: Human Type I Collagen Staining Kit

Yeast Viability Staining Kit (Green/Red)

31063-1 1kit
EUR 566.4
Description: Minimum order quantity: 1 unit of 1kit

Coomassie Brilliant Blue Gel Staining Kit

abx090653-1Kit 1 Kit
EUR 226.8

Hoechst 33342 / PI Double Staining Kit

abx097209-1Kit 1 Kit
EUR 292.8

Human FoxP3 Transcription Factor Staining Kit

OKTA00001 KIT
EUR 544.8
Description: Description of target: ;Species reactivity: ;Application: FC;Assay info: ;Sensitivity:

Human FoxP3 Transcription Factor Staining Kit

OKTA00004 KIT
EUR 544.8
Description: Description of target: ;Species reactivity: ;Application: FC;Assay info: ;Sensitivity:

Genorise® Alkaline Phosphatase Staining Kit

GR107045 100 tests
EUR 346.8

Fluorescein Active Caspase-12 Staining Kit

K2046-100 100 assays
EUR 686.4

Fluorescein Active Caspase-12 Staining Kit

K2046-25 25 assays
EUR 285.6

Fluorescein Active Caspase-2 Staining Kit

K2048-100 100 assays
EUR 686.4

Fluorescein Active Caspase-2 Staining Kit

K2048-25 25 assays
EUR 285.6

Fluorescein Active Caspase-3 Staining Kit

K2049-100 100 assays
EUR 686.4

Fluorescein Active Caspase-3 Staining Kit

K2049-25 25 assays
EUR 285.6

Fluorescein Active Caspase-8 Staining Kit

K2050-100 100 assays
EUR 686.4

Fluorescein Active Caspase-8 Staining Kit

K2050-25 25 assays
EUR 285.6

Fluorescein Active Caspase-9 Staining Kit

K2051-100 100 assays
EUR 686.4

Fluorescein Active Caspase-9 Staining Kit

K2051-25 25 assays
EUR 285.6

Red Active Caspase-3 Staining Kit

K2053-100 100 assays
EUR 686.4

Red Active Caspase-3 Staining Kit

K2053-25 25 assays
EUR 285.6

Red Active Caspase-8 Staining Kit

K2054-100 100 assays
EUR 686.4

Red Active Caspase-8 Staining Kit

K2054-25 25 assays
EUR 285.6

Red Active Caspase-9 Staining Kit

K2055-100 100 assays
EUR 686.4

Red Active Caspase-9 Staining Kit

K2055-25 25 assays
EUR 285.6

Stayright™ Purple HRP Staining Kit

45905 5 mL
EUR 109

Stayright™ Purple HRP Staining Kit

45906 50 mL
EUR 334

CaspGLOW? Fluorescein Active Caspase Staining Kit

K180-100 each
EUR 660

CaspGLOW? Fluorescein Active Caspase Staining Kit

K180-25 each
EUR 280.8

CaspGLOW? Red Active Caspase Staining Kit

K190-100 each
EUR 627.6

CaspGLOW? Red Active Caspase Staining Kit

K190-25 each
EUR 288

Lipid (Oil Red O) staining Kit

K580-24 each
EUR 542.4

Gel-FAST? Gel Staining/Destaining Kit

K901-40 each
EUR 210

Cas9-EGFP Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS420A-KIT 1 kit (10 rxn)
EUR 828

PinPoint-HR System for Platform Cell Line Generation & Retargeting (includes PIN400A-1, PIN200A-1, PIN510A-1, & PIN600A-1)

PIN400A-KIT 1 Kit
EUR 3357.6

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1358.4

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1358.4

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1358.4

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1358.4

Fluorescent Particles

FH-10040-2 2 mL
EUR 310.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-10052-2 2 mL
EUR 310.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-10056-10 10 mL
EUR 1022.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-10056-2 2 mL
EUR 310.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-10062-2 2 mL
EUR 310.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-10074-2 2 mL
EUR 310.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-10078-2 2 mL
EUR 310.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-2040-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-2045-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-2052-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-2056-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-2060-2 2 mL
EUR 261.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-2062-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-2070-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-3056-10 10 mL
EUR 802.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-3056-2 2 mL
EUR 237.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FH-5056-2 2 mL
EUR 237.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-0845-2 2 mL
EUR 279.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-0852-2 2 mL
EUR 225.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-10056-2 2 mL
EUR 310.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-10078-2 2 mL
EUR 310.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-2040-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-2045-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-2052-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-2056-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-2060-2 2 mL
EUR 261.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-2062-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-2068-2 2 mL
EUR 230.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-3068-2 2 mL
EUR 237.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-4070-2 2 mL
EUR 237.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-6056-2 2 mL
EUR 261.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FL-6068-2 2 mL
EUR 261.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-00552-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-00556-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-00558-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-00562-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-00570-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0245-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0252-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0256-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0257-2 2 mL
EUR 237.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0262-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0270-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0545-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0552-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0556-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0557-2 2 mL
EUR 237.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0558-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0562-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particles

FP-0570-2 2 mL
EUR 218.4
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.


Conclusion: Tan IIA reversed H2O2-induced reduction of cell proliferation, induction of cell apoptosis and G0 / G1 arrest in the cell reduction H9c2 by miR-133a-3p / EGFR axis. The findings suggest a molecular basis Tan IIA potential in treating patients with CAD.

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