Ischaemic preconditioning-induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway

Ischaemic preconditioning-induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway

Ischemia / reperfusion (I / R) injury can cause severe arrhythmias and myocardial damage worsens. Exosomes are small membrane vesicles that play a protective role of injury I / R myocardium. This study aims to explore the protective effects of ischemic preconditioning (IPC) induced serum exosomes (IPC-Ex) on the injury I / R myocardium in rats and the underlying mechanism. serum exosomes derived from rats IPC and quantified using bicinchoninic acid assay kit. IPC-Exo (50 mg) injected into the myocardium infarction immediately after the ligation. Rats were randomly divided into Sham, I / R, IPC-Ex + I / R, I / R + LY294002, and I / R + group IPC-Ex + LY294002. hemodynamic parameters measured by physiological recording.

Transthoracic echocardiography is used to detect heart function. Serum levels of creatine kinase-MB isomers, lactate dehydrogenase, aspartate transaminase, tumor necrosis factor-alpha, interleukin (IL) -1β, and IL-10 were detected by enzyme-linked immunosorbent assay. Triphenyl tetrazolium chloride staining was used to measure the size of myocardial infarction. Apoptosis in myocardial tissue was detected by TUNEL staining. Western blotting was used to detect the level of PI3K / AKT and proteins associated with apoptosis.

The results of our study indicate that treatment with IPC-Ex improved heart function and reduce the production of inflammatory factors, cardiomyocyte apoptosis, and myocardial infarct size. In addition, the IPC-Ex treatment promoted protein expression of Bcl-2, p-PI3K and p-AKT but inhibited the caspase-3 and Bax. However, treatment with LY294002 significantly reverse the increase in p-PI3K and p-AKT levels, hemodynamic improvement, and decreased production of inflammatory factor and apoptosis in group I / R + IPC IPC-Exo-Exo-induced. Taken together, our results suggest that the IPC-Ex can reduce the injury I / R via activating PI3K / AKT signaling pathway.

 Ischaemic preconditioning-induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway
Ischaemic preconditioning-induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway

Tanshinone IIA ameliorates the development of CAD Through Heart Settings H9c2 Cell Proliferation and Apoptosis by miR-133a-3p / EGFR Axis

Background: Coronary artery disease (CAD) leads to the world of death, serious threat to human health. Tanshinone IIA (Tan IIA), which can be extracted from Danshen, applied in the treatment of cardiovascular and cerebrovascular diseases. MicroRNAs (miRNAs, Mirs) plays an important role in cell proliferation and apoptosis of cells of the cardiovascular system. The purpose of this study was to explore the role of Tan IIA in CAD in vitro and the underlying molecular mechanisms.


Methods: Real-time polymerase chain reaction (RT-PCR) and Western blot used to detect miRNA / mRNA and protein, respectively. target genes miR-133a-3p searched at TargetScan and targeting relationships verified by dual-luciferase reporter assay. Cell proliferation was determined using cells Counting Kit-8 (CCK-8) and Edu labeling. Cell apoptosis was detected by flow cytometry and TUNEL staining.


Results: In this study, lower levels of miR-133a-3p and epidermal growth factor receptor that is higher (EGFR, the target of miR-133a-3p) level found in H2O2-induced cell H9c2. In addition, Tan IIA-regulated miR-133a-3p and downregulated the expression of EGFR. In addition, Tan IIA promoted cell proliferation and reduced apoptosis and increased G0 / G1, which is reversed with inhibitors of miR-133a-3p, while siRNA-EGFR eliminate the effects caused by miR-133a-3p in H2O2-induced cell H9c2.

Beta-Galactosidase Staining Kit

K802-250
EUR 294

Beta-Galactosidase Staining Kit

K2182-250 250 assays
EUR 293

StemTAG Alkaline Phosphatase Staining Kit (Red)

CBA-300 100 assays
EUR 461
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Staining Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining.

StemTAG Alkaline Phosphatase Staining Kit (Purple)

CBA-306 100 assays
EUR 461
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Staining Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining.

Cellular Senescence Detection Kit (SA-?-Gal Staining)

CBA-230 50 assays
EUR 519
Description: Our Cellular Senescence Staining Kit provides an efficient method to visualize Senescence Associated (SA) ß-galactosidase. SA-ß-Gal catalyzes the hydrolysis of X-gal, which produces a blue color in senescent cells. Visualize results with a standard light microscope.

Cellular Senescence Detection Kit (SA-?-Gal Staining)

CBA-230-5 5 x 50 assays
EUR 2051
Description: Our Cellular Senescence Staining Kit provides an efficient method to visualize Senescence Associated (SA) ß-galactosidase. SA-ß-Gal catalyzes the hydrolysis of X-gal, which produces a blue color in senescent cells. Visualize results with a standard light microscope.

OxiSelect DNA Double-Strand Break (DSB) Staining Kit

STA-321 100 assays
EUR 659
Description: Double-strand breaks (DSB) in DNA are among the most dangerous types of DNA damage occuring within cells. One of the earliest cellular responses to double-strand breaks is the phosphorylation of a histone variant, H2AX, at the sites of DNA damage. Within seconds Ser139 is phosphorylated when DSBs are induced in mammalian cells. Phosphorylation of this serine residue causes chromatin condensation and appears to play a critical role in the recruitment of repair or damage-signaling factors to the DNA damage sites. The OxiSelect DNA Double-Strand Break Staining Kit provides an easy-to-use method for detecting the presence of DSBs in cells cultured in microtiter plates. Double strand breaks can be detected in just a few hours by immunofluorescence staining of the phosphorylated histone H2AX.

StemTAG Alkaline Phosphatase Staining and Activity Assay Kit, Colorimetric

CBA-302 2 x 100 assays
EUR 641
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Activity Assay Combo Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining as well as in a 96-well plate with either colorimetric or fluorescence detection.

StemTAG Alkaline Phosphatase Staining and Activity Assay Kit, Fluorometric

CBA-308 2 x 100 assays
EUR 705
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Activity Assay Combo Kits provide reagents for monitoring alkaline phosphatase activity via immunocytochemistry staining as well as in a 96-well plate with either colorimetric or fluorescence detection.

OxiSelect Cellular UV-Induced DNA Damage Staining Kit (CPD)

STA-327 96 assays
EUR 659
Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of cyclobutane pyrimidine dimers (CPD) by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-CPD antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope.

OxiSelect DNA Double Strand Break (DSB) Staining Kit, Trial Size

STA-321-T 20 assays
EUR 351
Description: Double-strand breaks (DSB) in DNA are among the most dangerous types of DNA damage occuring within cells. One of the earliest cellular responses to double-strand breaks is the phosphorylation of a histone variant, H2AX, at the sites of DNA damage. Within seconds Ser139 is phosphorylated when DSBs are induced in mammalian cells. Phosphorylation of this serine residue causes chromatin condensation and appears to play a critical role in the recruitment of repair or damage-signaling factors to the DNA damage sites. The OxiSelect DNA Double-Strand Break Staining Kit provides an easy-to-use method for detecting the presence of DSBs in cells cultured in microtiter plates. Double strand breaks can be detected in just a few hours by immunofluorescence staining of the phosphorylated histone H2AX.

OxiSelect Cellular UV-Induced DNA Damage Staining Kit (6-4PP)

STA-329 96 assays
EUR 659
Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of 6-4PP structures in DNA by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-6-4PP antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope.

Live/Dead Cell Staining Kit

55R-1434 100 tests
EUR 638
Description: Live/Dead Cell Staining Kit for use in the research laboratory

Live-Dead Cell Staining Kit

K501-100
EUR 468

Live-Dead Cell Staining Kit

K2081-100 100 staining
EUR 460

OxiSelect Cellular UV-Induced DNA Damage Staining Kit (CPD), Trial Size

STA-327-T 32 assays
EUR 351
Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of cyclobutane pyrimidine dimers (CPD) by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-CPD antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope.

OxiSelect Cellular UV-Induced DNA Damage Staining Kit (6-4PP), Trial Size

STA-329-T 32 assays
EUR 351
Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of 6-4PP structures in DNA by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-6-4PP antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope.

DAPI Staining Kit

abx097206-1Kit 1 Kit
EUR 230
  • Shipped within 5-10 working days.

PI Staining Kit

abx097208-1Kit 1 Kit
EUR 230
  • Shipped within 5-10 working days.

Beta Hexosaminidase Activity Assay Kit

MET-5095 100 assays
EUR 508

EZCell? Intracellular Zinc Staining Kit (Cell-Based)

K525-50
EUR 566

Autophagy/Cytotoxicity Dual Staining Kit (Cell-Based)

K449-50
EUR 544

Lysosomal Cytotoxicity Dual Staining Kit (Cell-Based)

K458-50
EUR 572

Human Beta 2 Microglobulin ELISA Kit

PRB-5038 96 assays
EUR 572
Description: Our Human Beta 2 Microglobulin ELISA Kit is a sandwich ELISA for the detection of human beta 2 microglobulin in plasma, serum, lysates, and other biological fluids. Samples or standards are added to an anti-b2M antibody coated plate followed by the addition of an HRP conjugated anti-human b2M antibody. The absorbance is read at 450nm and the level of b2M in samples is determined based on the provided human b2M standard curve.

CometAssay Silver Staining Kit

4254-200-K 200 Tests
EUR 325.8

Hoechst 33342 Staining Kit

abx097207-1Kit 1 Kit
EUR 230
  • Shipped within 5-10 working days.

Human Histochemistry Staining Kit

20-abx299039
  • EUR 871.00
  • EUR 1219.00
  • EUR 565.00
  • 150 tests
  • 500 tests
  • 50 tests
  • Shipped within 1 week.

Alkaline Phosphatase Staining Kit

K2035-50 50 assays
EUR 379

Cell Navigator™ Lysosome Staining Kit *NIR Fluorescence*

22652 500 Tests
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Lysosome Staining Kit *Blue Fluorescence*

22655 500 Tests
EUR 176
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Lysosome Staining Kit *Green Fluorescence*

22656 500 Tests
EUR 176
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Lysosome Staining Kit *Orange Fluorescence*

22657 500 Tests
EUR 176
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Lysosome Staining Kit *Red Fluorescence*

22658 500 Tests
EUR 176
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Mitochondrion Staining Kit *Blue Fluorescence*

22665 500 Assays
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Mitochondrion Staining Kit *Green Fluorescence*

22666 500 Assays
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Mitochondrion Staining Kit *Orange Fluorescence*

22667 500 Assays
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Mitochondrion Staining Kit *Red Fluorescence*

22668 500 Assays
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Mitochondrion Staining Kit *NIR Fluorescence*

22670 500 Assays
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Beta-Hydroxybutyrate (Ketone Body) Assay Kit (Colorimetric)

MET-5082 100 assays
EUR 508

Beta-Hydroxybutyrate (Ketone Body) Assay Kit (Fluorometric)

MET-5083 100 assays
EUR 508

Cell Navigator™ Cell Plasma Membrane Staining Kit *Orange Fluorescence*

22680 500 Tests
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Cell Plasma Membrane Staining Kit *Red Fluorescence*

22681 500 Tests
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Fluorescent Particle Kit

FA-2552-6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particle Kit

FA-3558-6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particle Kit

FB-2552-6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particle Kit

FB-3558-6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particle Kit

FX-3552-6K 6x1 mL
EUR 360
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent Particle Kit

FX-3552-9K 9X1 mL
EUR 563
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Fluorescent

FPAK-3058--9K 9X1 mL
EUR 563
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Frit Kit

FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Nerve Terminal Staining Kit V

70034 1SET
EUR 509
Description: Minimum order quantity: 1 unit of 1SET

CaspGLOW Active Caspase Staining Kit

55R-1292 25 assays
EUR 296
Description: Caspase Staining Kit for use activity in the research laboratory

Blue-Color AP Staining Kit

AP100B-1 50 Assays
EUR 262
  • Category: Stem Cells

Dual- Color AP Staining Kit

AP100D-1 100 Assays
EUR 412
  • Category: Stem Cells

Red-Color AP Staining Kit

AP100R-1 50 Assays
EUR 262
  • Category: Stem Cells

Fluorescein Active Caspase Staining Kit

K2047-25 25 assays
EUR 238

Red Active Caspase Staining Kit

K2052-100 100 assays
EUR 572

Red Active Caspase Staining Kit

K2052-25 25 assays
EUR 238

DNA Ploidy Analysis Staining Kit

K1439-1
EUR 588

DNA Ploidy Analysis Staining Kit

K1439-5
EUR 2002

Cell Navigator™ Lysosome Staining Kit *Deep Red Fluorescence*

22659 500 Tests
EUR 176
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Mitochondrion Staining Kit *Deep Red Fluorescence*

22669 500 Assays
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Column Packing Kit

PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266

PinPoint-HR System for Platform Cell Line Generation & Retargeting (includes PIN400A-1, PIN200A-1, PIN510A-1, & PIN600A-1)

PIN400A-KIT 1 Kit
EUR 2798
  • Category: PinPoint Integrase Tools

EasyComp Fluorescent Particles Kit

ECFP-K1 mL
EUR 299
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

EasyComp Fluorescent Particles Kit

ECFP-K2 mL
EUR 370
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

EasyComp Fluorescent Particles Kit

ECFP-K3 mL
EUR 370
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

EasyComp Fluorescent Particles Kit

ECFP-K4 mL
EUR 584
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

EasyComp Fluorescent Particles Kit

ECFP-K5 mL
EUR 533
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Carboxyl Fluorescent Particle Kit

CFA-2552-6K 6x1 mL
EUR 462
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFA-2558-6K 6x1 mL
EUR 462
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFA-3558-6K 6x1 mL
EUR 462
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFB-2552-6K 6x1 mL
EUR 462
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFB-2558-6K 6x1 mL
EUR 462
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particle Kit

CFB-3558-6K 6x1 mL
EUR 462
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Carboxyl Fluorescent Particles Kit

CFX-3552-9K 9X1 mL
EUR 573
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

AccuCount Fluorescent Particle Kit

ACFP-50-4K 4X1mL
EUR 517
Description: Flow Cytometry Particles For Absolute Cell Counting

Fluorescent Particle Array Kit

FPAK-4058--10K 10 mL
EUR 563
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Thiol Fluorescent Detection Kit

K005-F1 1x96 well plate
EUR 318

Glutathione Fluorescent Detection Kit

K006-F1 1x96 well plate
EUR 354

Glutathione Reductase Fluorescent Kit

K009-F1 1x96 well plate
EUR 349

Streptavidin Fluorescent Particle Kit

SVFA-2552--6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin Fluorescent Particle Kit

SVFA-2558--6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin Fluorescent Particle Kit

SVFB-2552--6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin Fluorescent Particle Kit

SVFB-2558--6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Biotin Fluorescent Particle Kit

TFA-3558-6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Biotin Fluorescent Particle Kit

TFB-3558-6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

PinPoint-FC System for Platform Cell Line Generation & Retargeting (includes PIN300A-1, FC200PA-1, PIN200A-1, PIN510A-1, & PIN600A-1)

PIN300A-KIT 1 Kit
EUR 2798
  • Category: PinPoint Integrase Tools

Cell Navigator™ Live Cell Endoplasmic Reticulum (ER) Staining Kit *Green Fluorescence*

22635 100 Tests
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cell Navigator™ Live Cell Endoplasmic Reticulum (ER) Staining Kit *Red Fluorescence*

22636 100 Tests
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110
  • Category: Cas9

Yeast Viability Staining Kit (Green/Red)

31063-1 1kit
EUR 472
Description: Minimum order quantity: 1 unit of 1kit

CaspGLOW Active Caspase 12 Staining Kit

55R-1291 25 assays
EUR 282
Description: Caspase 12 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 2 Staining Kit

55R-1293 25 assays
EUR 284
Description: Caspase 2 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 3 Staining Kit

55R-1294 25 assays
EUR 296
Description: Caspase 3 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 8 Staining Kit

55R-1295 25 assays
EUR 296
Description: Caspase 8 Staining Kit for use activity in the research laboratory

CaspGLOW Active Caspase 9 Staining Kit

55R-1296 25 assays
EUR 296
Description: Caspase 9 Staining Kit for use activity in the research laboratory


Conclusion: Tan IIA reversed H2O2-induced reduction of cell proliferation, induction of cell apoptosis and G0 / G1 arrest in the cell reduction H9c2 by miR-133a-3p / EGFR axis. The findings suggest a molecular basis Tan IIA potential in treating patients with CAD.

Leave A Comment